COBAS® INTEGRA 400 plus 

COBAS INTEGRA 400 plus is a fully automated, random access, sample discrete, multi-analyte analyzer.

This table top system employs four different technologies namely absorption photometry, fluorescence polarization immuno assay (FPIA), Immuno-turbidimetry & Potentiometry.

Due to the multiple technologies employed the one single platform, the system can accommodate wide menu with over 100 types of assays on board.


Customer Benefits

  • System concept reduces sample splitting (decreasing manual errors)
  • Workflow optimization within the lab
  • Supports continuous or batch loading, depending on lab operation
  • Ensures correct sample pipetting with clot detection
  • Multilingual Graphic User Interface
  • Extensive multilingual Online-Help
  • Programmable BOD (begin of day) tasks to minimize daily instrument preparation time.



  • Four different measuring technologies on single platform:
    • Fluorescence Polarization
    • Immuno Turbidimetry
    • Absorbance Photometry
    • Potentiometry (direct & indirect)
  • Clot detection system
  • Ready to use reagents in a unique reagent carrier
  • Long reagent on-board stability
  • Minimal calibration frequency (typically each lot)
  • Barcode reading of all relevant reagent information
  • Large expanding menu (> 100 assays already available)
  • On board capacity of 32 assays
  • Loading / reloading during the run
  • User friendly intuitive user interface
  • Wide Menu on board:
    • Substrates & Enzymes
    • Specific proteins
    • Therapeutic Drug Monitoring
    • Drugs of Abuse test
    • Electrolytes